Content Handbook M

Outline of method

Clodinafop-propargyl is a chiral compound (R-enantiomer). Hence two methods are used to determine the chemical and the enantiomeric purity. The first analytical procedure determines the sum of both enantiomers.
The sum of clodinafop-propargyl (R-enantiomer) and the S-enantiomer is determined by reversed phase high performance liquid chromatography using UV detection at 305 nm and external standardisation. By a separate method clodinafop-propargyl is separated from the S-enantiomer by chiral phase high performance liquid chromatography using UV detection at 230 nm and the R- enantiomer fraction is determined.

Scope

The method is usable for TC, WP and EC-formulations.